3-(1-Piperazinyl)-1,2-benzisothiazole
- Name3-(1-Piperazinyl)-1,2-benzisothiazole
- CAS87691-87-0
- Purity99%
Product Details
Cosmetics Grade 3-(1-Piperazinyl)-1,2-benzisothiazole 87691-87-0 For Sale with Good Price
- Molecular Formula:C11H13N3S
- Molecular Weight:219.31
- Vapor Pressure:0.000323mmHg at 25°C
- Melting Point:89.0 to 93.0 °C
- Refractive Index:1.655
- Boiling Point:320.2 °C at 760 mmHg
- PKA:8.52±0.10(Predicted)
- Flash Point:147.4 °C
- PSA：56.40000
- Density:1.256 g/cm3
- LogP:2.09970
3-(1-Piperazinyl)-1,2-benzisothiazole(Cas 87691-87-0) Usage
InChI:InChI=1/C11H13N3S/c1-2-4-10-9(3-1)11(13-15-10)14-7-5-12-6-8-14/h1-4,12H,5-8H2
87691-87-0 Relevant articles
Benzisothiazole compound and preparation method thereof and purpose of benzisothiazole compound for treating depression
-
Paragraph 0054; 0056; 0062; 0063, (2018/09/12)
The invention discloses a benzisothiazol...
A key intermediate for the preparation of ziprasidone
-
, (2018/04/03)
The present invention relates to a zipra...
Synthesis and biological evaluation of novel isoxazolines linked via piperazine to 2- benzoisothiazoles as potent apoptotic agents
Byrappa, Sathish,Harsha Raj,Kungyal, Tenzin,Kudva N, Narayana U.,Salimath, Bharathi P.,Lokanatha Rai
, p. 218 - 224 (2016/11/23)
Synthesis of 3-(4-((3-Phenyl-4,5-dihydro...
Aralkylpiperidine (or piperazinecarboxylic) and its derivatives used for treating hypercalcemia schinzopherenia
-
Paragraph 0116, (2018/12/01)
PROBLEM TO BE SOLVED: To provide an agen...
87691-87-0 Process route
-
-
110-85-0
piperazine
-
-
7716-66-7
3-chloro-1,2-benzisothiazole
-
-
87691-87-0
3-(1-piperazinyl)-1,2-benzisothiazole
| Conditions | Yield |
|---|---|
|
In
ethanol;
at 80 ℃;
for 36h;
|
85% |
|
In
ethanol;
at 80 ℃;
for 18h;
|
79.6% |
|
at 125 ℃;
for 24h;
|
68% |
|
In
tert-butyl alcohol;
Inert atmosphere;
Reflux;
|
65% |
|
at 120 ℃;
for 12h;
|
56.4% |
|
at 125 ℃;
for 24h;
|
24% |
|
piperazine; 3-chloro-1,2-benzisothiazole;
In
tert-butyl alcohol;
at 110 - 130 ℃;
for 16h;
With
sodium hydroxide;
In
water; toluene; tert-butyl alcohol;
at 25 - 35 ℃;
pH=12 - 14;
|
|
|
piperazine; 3-chloro-1,2-benzisothiazole;
In
tert-butyl alcohol;
for 15h;
Heating / reflux;
With
water;
In
tert-butyl alcohol;
|
|
|
at 125 ℃;
for 24h;
|
|
|
at 125 ℃;
for 24h;
|
-
![3-[bis(hydroxyethyl)]amino-1,2-benzisothiazole](/upload/2026/7/49e1e87bd7f44fd8ae722a4d47f2d63c_84e7f776-430d-4682-a16b-0c59450d4a5c.png)
-
1384511-83-4
3-[bis(hydroxyethyl)]amino-1,2-benzisothiazole
-
-
87691-87-0
3-(1-piperazinyl)-1,2-benzisothiazole
| Conditions | Yield |
|---|---|
|
3-[bis(hydroxyethyl)]amino-1,2-benzisothiazole;
With
methanesulfonyl chloride; triethylamine;
In
methanol; acetonitrile;
at 0 - 20 ℃;
With
ammonium hydroxide;
Reflux;
|
71% |
87691-87-0 Upstream products
-
110-85-0
piperazine
-
7716-66-7
3-chloro-1,2-benzisothiazole
-
19602-82-5
2,2'-dithiodibenzoic acid dichloride
-
2634-33-5
1,2-benzisothiazolin-3-one
87691-87-0 Downstream products
-
87691-91-6
tiospirone
-
131779-46-9
1,1-dimethylethyl 4-(1,2-benzisothiazol-3-yl)-1-piperazinecarboxylate
-
118856-18-1
8-<<3-<4-(1,2-benzisothiazol-3-yl)-1-piperazinyl>propyl>oxy>-8-azaspiro<4.5>decane-7,9-dione hydrochloride
-
155289-55-7
(+/-)-trans-2-(4-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)butyl)-4a,5,6,7,8,8a-hexahydro-1(2H)phthalazinone
Related products
-
EC 2.6.1.2CAS：9000-86-6
-
IHT-PI 432CAS：104558-95-4
-
2-hydroxypropane-1-sulfonic acidCAS：1561-96-2
-
POLYBENZIMIDAZOLE
CAS：25928-81-8