Pirlimycin

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Pirlimycin

  • Name Pirlimycin
  • CAS 79548-73-5
  • Purity 99%
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1.What is the Pirlimycin ?

Pirlimycin is a semi-synthetic lincosamide antibiotic derived from clindamycin. It is more hydrophobic than clindamycin and exhibits increased potency against various significant pathogens. As a member of the lincosamide family, Pirlimycin possesses broad-spectrum antibiotic properties, demonstrating effectiveness against anaerobic bacteria and protozoans. Its mechanism of action involves binding to the 23S ribosomal subunit, thereby inhibiting protein synthesis. Although Pirlimycin has not been as extensively researched as older lincosamides, it holds promise in the field of antibiotic therapy.

2.What is the CAS number for Pirlimycin ?

The CAS number of Pirlimycin is 79548-73-5.

3.What are another words for Pirlimycin ?

Synonyms?for?Pirlimycin 79548-73-5:L-threo-a-D-galacto-Octopyranoside, methyl7-chloro-6,7,8-trideoxy-6-[[(4-ethyl-2-piperidinyl)carbonyl]amino]-1-thio-,(2S-cis)-;Pirlimycin;

4.What is Pirlimycin (79548-73-5) used for?

Pirlimycin is a semi-synthetic lincosamide prepared from clindamycin by hydrolysing the propyl N-methylproline and re-annealing a 4-ethylpipecolic acid. Pirlimycin is more hydrophobic than clindamycin and is more potent against a number of important pathogens. Like other members of the lincosamide family, pirlimycin is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Pirlimycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis. Pirlimycin has been less extensively researched than the older lincosamides.

InChI:InChI=1/C17H31ClN2O5S/c1-4-9-5-6-19-10(7-9)16(24)20-11(8(2)18)15-13(22)12(21)14(23)17(25-15)26-3/h8-15,17,19,21-23H,4-7H2,1-3H3,(H,20,24)/t8-,9+,10-,11+,12-,13+,14+,15+,17+/m0/s1

Relevant articles related to Pirlimycin:

Article

Source

Synthesis and antimicrobial actvity of clindamycin analogues: Pirlimycin, a potent antibacterial agent

Birkenmeyer,Kroll,Lewis,et al.

, p. 216 - 223 (2007/10/02)

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