acetyl Methanesulfonate

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acetyl Methanesulfonate

  • Name acetyl Methanesulfonate
  • CAS 5539-53-7
  • Purity 99%
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Product Details

Factory Sells Best Quality acetyl Methanesulfonate 5539-53-7 with USP

  • Molecular Formula: C3H6O4S
  • Molecular Weight: 138.144
  • Vapor Pressure: 0.298mmHg at 25°C 
  • Refractive Index: 1.431 
  • Boiling Point: 202.1 °C at 760 mmHg 
  • Flash Point: 76 °C 
  • PSA: 68.82000 
  • Density: 1.346 g/cm3 
  • LogP: 0.58990 

acetyl Methanesulfonate(Cas 5539-53-7) Usage

Purification Methods

The main impurity is methanesulfonic acid. Reflux it with redistilled acetyl chloride for 6-10hours, i.e. until no further HCl is absorbed in a trap, and exclude moisture. Distil off excess of AcCl and carefully distil it below 0.001mm with the bath temperature below 120o to give the anhydride as a pale yellow oil which solidifies below 0o. Below ~130o it gives the disulfonic anhydride, and above ~130o polymers are formed, and it is used for cleaving ethers [Preparation, IR, NMR: Karger & Mazur J Org Chem 36 528, 532 1971]. [Beilstein 2 H 166, 2 III 349.]

InChI:InChI=1/C3H6O4S/c1-3(4)7-8(2,5)6/h1-2H3

5539-53-7 Relevant articles

SYNTHESIS

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Page/Page column 7-8, (2008/12/07)

The present invention provides a method ...

α-(TRIALKYLSILYL)-, α-(TRIALKYLGERMYL)-, AND α-(TRIALKYLSTANNYL)-ALKANESULFONIC ESTERS AND AMIDES AND TRIMETHYLSILYL SULFONATES: THEIR SYNTHESIS AND SOME OF THEIR REACTIONS

Shipov, A. G.,Baukov, Yu. I.

, p. 1642 - 1657 (2007/10/02)

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5539-53-7 Process route

Methyl methanesulfonate
66-27-3

Methyl methanesulfonate

Acetyl bromide
506-96-7

Acetyl bromide

methyl bromide
74-83-9

methyl bromide

Acetyl methanesulfonate
5539-53-7

Acetyl methanesulfonate

Conditions
Conditions Yield
at 100 - 110 ℃; for 1h;
55%
95%
methanesulphonyltrifluoroacetic anhydride
93370-09-3

methanesulphonyltrifluoroacetic anhydride

acetyl chloride
75-36-5

acetyl chloride

trifluoracetyl chloride
354-32-5

trifluoracetyl chloride

Acetyl methanesulfonate
5539-53-7

Acetyl methanesulfonate

Conditions
Conditions Yield
at 50 ℃; for 1h; Yield given;
86.5%
at 50 ℃; for 1h; Yields of byproduct given;
86.5%

5539-53-7 Upstream products

  • 66-27-3
    66-27-3

    Methyl methanesulfonate

  • 506-96-7
    506-96-7

    Acetyl bromide

  • 93370-09-3
    93370-09-3

    methanesulphonyltrifluoroacetic anhydride

  • 75-36-5
    75-36-5

    acetyl chloride

5539-53-7 Downstream products

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    62609-70-5

    bis-methanesulfonyloxymethyl ether

  • 25289-73-0
    25289-73-0

    methoxymethyl methanesulfonate

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    72655-76-6

    Acetic acid 3-bromomethyl-cyclohex-1-enyl ester

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    108869-70-1

    2-Acetyl-5-(6-O-acetyl-2,3,4-tri-O-benzyl-α-D-glucopyranosyl)furan

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